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Target
Neuraminidase
Ligand
BDBM50176807
Substrate
n/a
Meas. Tech.
ChEMBL_1579101 (CHEMBL3811449)
IC50
2900±n/a nM
Citation
 Kumar, V; Tan, KP; Wang, YM; Lin, SW; Liang, PH Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors. Bioorg Med Chem 24:3035-3042 (2016) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NA | NRAM_I33A0
Type:
PROTEIN
Mol. Mass.:
49687.56
Organism:
Influenza A virus
Description:
ChEMBL_1347422
Residue:
453
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVAGQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWDPNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETIWTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
  
Inhibitor
Name:
BDBM50176807
Synonyms:
CHEMBL3808658
Type:
Small organic molecule
Emp. Form.:
C27H16ClFN2O4
Mol. Mass.:
486.878
SMILES:
OC(=O)c1ccc(Cl)cc1-c1ccc(\C=C2/C(=O)N(N=C2c2ccccc2)c2ccc(F)cc2)o1 |c:20|
Structure:
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