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Target
C-C chemokine receptor type 9
Ligand
BDBM50178718
Substrate
n/a
Meas. Tech.
ChEMBL_1583874 (CHEMBL3815306)
IC50
451±n/a nM
Citation
 Pandya, BA; Baber, C; Chan, A; Chamberlain, B; Chandonnet, H; Goss, J; Hopper, T; Lippa, B; Poutsiaka, K; Romero, J; Stucka, S; Varoglu, M; Zhang, J; Zhang, X Discovery of indole inhibitors of chemokine receptor 9 (CCR9). Bioorg Med Chem Lett 26:3322-3325 (2016) [PubMed]  Article 
Target
Name:
C-C chemokine receptor type 9
Synonyms:
CCR9 | CCR9_HUMAN | GPR28
Type:
PROTEIN
Mol. Mass.:
42023.90
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1510356
Residue:
369
Sequence:
MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHTLIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLLETTSGALSL
  
Inhibitor
Name:
BDBM50178718
Synonyms:
CHEMBL3814598
Type:
Small organic molecule
Emp. Form.:
C19H19ClN2O2
Mol. Mass.:
342.819
SMILES:
CC(C)(C)c1ccc(Cn2c(cc3cccc(Cl)c23)C(O)=O)cn1
Structure:
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