Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, adipocyte
Ligand
BDBM50187495
Substrate
n/a
Meas. Tech.
ChEMBL_1589882 (CHEMBL3830762)
Ki
4300±n/a nM
Citation
 Zhou, Y; Nie, T; Zhang, Y; Song, M; Li, K; Ding, M; Ding, K; Wu, D; Xu, Y The discovery of novel and selective fatty acid binding protein 4 inhibitors by virtual screening and biological evaluation. Bioorg Med Chem 24:4310-4317 (2016) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, adipocyte
Synonyms:
A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4)
Type:
Enzyme
Mol. Mass.:
14719.23
Organism:
Homo sapiens (Human)
Description:
P15090
Residue:
132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
  
Inhibitor
Name:
BDBM50187495
Synonyms:
CHEMBL3828660
Type:
Small organic molecule
Emp. Form.:
C16H16ClNO5S
Mol. Mass.:
369.82
SMILES:
CCCOc1cc(ccc1Cl)S(=O)(=O)Nc1ccc(cc1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: