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Target
Carbonic anhydrase 2
Ligand
BDBM50204560
Substrate
n/a
Meas. Tech.
ChEMBL_1627626 (CHEMBL3870147)
Ki
55±n/a nM
Citation
 Arslan, T; Türko?lu, EA; ?entürk, M; Supuran, CT Synthesis and carbonic anhydrase inhibitory properties of novel chalcone substituted benzenesulfonamides. Bioorg Med Chem Lett 26:5867-5870 (2016) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50204560
Synonyms:
CHEMBL3955905
Type:
Small organic molecule
Emp. Form.:
C22H19N3O5S
Mol. Mass.:
437.468
SMILES:
COc1ccc(\C=C\C(=O)c2ccc(O)c(c2)\N=N\c2ccc(cc2)S(N)(=O)=O)cc1
Structure:
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