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Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50036868
Substrate
n/a
Meas. Tech.
ChEMBL_1540 (CHEMBL616363)
IC50
1.0±n/a nM
Citation
  Fluorescent probes for 5-HT1A receptors: Synthesis and characterization of 5-methoxy-3-[n-propyl(4-n-aminobutyl)] amino-3,4-dihydro-2H-1-benzopyran derivatives Bioorg Med Chem Lett 3:1935-1940 (1993)   
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM50036868
Synonyms:
2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl}-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one; compound with oxalic acid | CHEMBL51561
Type:
Small organic molecule
Emp. Form.:
C24H30N2O5S
Mol. Mass.:
458.57
SMILES:
CCCN(CCCCN1C(=O)c2ccccc2S1(=O)=O)C1COc2cccc(OC)c2C1
Structure:
Search PDB for entries with ligand similarity: