Reaction Details Report a problem with these data
Target
D(4) dopamine receptor
Ligand
BDBM50213846
Substrate
n/a
Meas. Tech.
ChEMBL_61327 (CHEMBL670102)
Ki
16±n/a nM
Citation
  TBA Bioorg Med Chem Lett 6:1227-1232 (1996)   
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50213846
Synonyms:
CHEMBL20251
Type:
Small organic molecule
Emp. Form.:
C20H32ClN3O2
Mol. Mass.:
381.94
SMILES:
COc1cc(Cl)ccc1N1CCN(CCCCNC(=O)C(C)(C)C)CC1
Structure:
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