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Target
Phosphatidylinositol 4-kinase type 2-alpha
Ligand
BDBM50009680
Substrate
n/a
Meas. Tech.
ChEMBL_152907 (CHEMBL758630)
Ki
6000±n/a nM
Citation
 Young, RC; Jones, M; Milliner, KJ; Rana, KK; Ward, JG Purine derivatives as competitive inhibitors of human erythrocyte membrane phosphatidylinositol 4-kinase. J Med Chem 33:2073-80 (1990) [PubMed]  Article 
Target
Name:
Phosphatidylinositol 4-kinase type 2-alpha
Synonyms:
P4K2A_HUMAN | PI4K2A | Phosphatidylinositol 4-kinase type 2-alpha | Phosphatidylinositol 4-kinase type II-alpha
Type:
PROTEIN
Mol. Mass.:
54030.26
Organism:
Homo sapiens (Human)
Description:
ChEMBL_104812
Residue:
479
Sequence:
MDETSPLVSPERAQPPDYTFPSGSGAHFPQVPGGAVRVAAAAGSGPSPPGSPGHDRERQPLLDRARGAAAQGQTQTVAAQAQALAAQAAAAAHAAQAHRERNEFPEDPEFEAVVRQAELAIERCIFPERIYQGSSGSYFVKDPQGRIIAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDSSSSRDTDWVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARSHQRSSSESYTQSFQSRKPFFSWW
  
Inhibitor
Name:
BDBM50009680
Synonyms:
6-Amino-9-cyclopentyl-9H-purine | 9-Cyclopentyl-9H-adenine | 9-Cyclopentyl-9H-purin-6-ylamine | CHEMBL294590
Type:
Small organic molecule
Emp. Form.:
C10H13N5
Mol. Mass.:
203.2437
SMILES:
Nc1ncnc2n(cnc12)C1CCCC1
Structure:
Search PDB for entries with ligand similarity: