Reaction Details Report a problem with these data
Target
Phosphatidylinositol 4-kinase type 2-alpha
Ligand
BDBM50208876
Substrate
n/a
Meas. Tech.
ChEMBL_152907 (CHEMBL758630)
Ki
99900±n/a nM
Citation
 Young, RC; Jones, M; Milliner, KJ; Rana, KK; Ward, JG Purine derivatives as competitive inhibitors of human erythrocyte membrane phosphatidylinositol 4-kinase. J Med Chem 33:2073-80 (1990) [PubMed]  Article 
Target
Name:
Phosphatidylinositol 4-kinase type 2-alpha
Synonyms:
P4K2A_HUMAN | PI4K2A | Phosphatidylinositol 4-kinase type 2-alpha | Phosphatidylinositol 4-kinase type II-alpha
Type:
PROTEIN
Mol. Mass.:
54030.26
Organism:
Homo sapiens (Human)
Description:
ChEMBL_104812
Residue:
479
Sequence:
MDETSPLVSPERAQPPDYTFPSGSGAHFPQVPGGAVRVAAAAGSGPSPPGSPGHDRERQPLLDRARGAAAQGQTQTVAAQAQALAAQAAAAAHAAQAHRERNEFPEDPEFEAVVRQAELAIERCIFPERIYQGSSGSYFVKDPQGRIIAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDSSSSRDTDWVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARSHQRSSSESYTQSFQSRKPFFSWW
  
Inhibitor
Name:
BDBM50208876
Synonyms:
1H-Pyrazolo[3,4-d]pyrimidin-4-ylamine | 4-aminopyrazolo[3,4-d]pyrimidine | CHEMBL388593
Type:
Small organic molecule
Emp. Form.:
C5H5N5
Mol. Mass.:
135.1267
SMILES:
Nc1ncnc2n[nH]cc12
Structure:
Search PDB for entries with ligand similarity: