Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50009561
Substrate
n/a
Meas. Tech.
ChEMBL_39798 (CHEMBL876771)
IC50
>50000±n/a nM
Citation
 Cushman, M; Nagarathnam, D; Gopal, D; Chakraborti, AK; Lin, CM; Hamel, E Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization. J Med Chem 34:2579-88 (1991) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50009561
Synonyms:
(E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | 2-Methoxy-5-[(E)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol | 2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol | 2-methoxy-5-(3,4,5-trimethoxystyryl)phenol | 2-methoxy-5-[(E)-2-(3,4,5-trimethoxyphenyl)vinyl]phenol | CHEMBL36455 | E-Combretastatin A-4 | trans-2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol | trans-combretastatin A-4
Type:
Small organic molecule
Emp. Form.:
C18H20O5
Mol. Mass.:
316.3484
SMILES:
COc1ccc(\C=C\c2cc(OC)c(OC)c(OC)c2)cc1O
Structure:
Search PDB for entries with ligand similarity: