Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50233601
Substrate
n/a
Meas. Tech.
ChEMBL_1651007 (CHEMBL4000262)
Ki
0.100000±n/a nM
Citation
 Nikas, SP; Sharma, R; Paronis, CA; Kulkarni, S; Thakur, GA; Hurst, D; Wood, JT; Gifford, RS; Rajarshi, G; Liu, Y; Raghav, JG; Guo, JJ; Järbe, TU; Reggio, PH; Bergman, J; Makriyannis, A Probing the carboxyester side chain in controlled deactivation (-)-d(8)-tetrahydrocannabinols. J Med Chem 58:665-81 (2015) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38220.43
Organism:
MOUSE
Description:
P47936
Residue:
347
Sequence:
MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
  
Inhibitor
Name:
BDBM50233601
Synonyms:
CHEMBL4062745
Type:
Small organic molecule
Emp. Form.:
C25H33NO4
Mol. Mass.:
411.5338
SMILES:
[H][C@@]12CC(C)=CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)C(C)(C)C(=O)OCCCCC#N |r,c:4|
Structure:
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