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TargetDopamine receptor D2L/neurotensin receptor NTS1
LigandBDBM50056443
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1661599
Ki 46±n/a nM
Citation Bonifazi, AYano, HEllenberger, MPMuller, LKumar, VZou, MFCai, NSGuerrero, AMWoods, ASShi, LNewman, AH Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D J Med Chem60:2890-2907 (2017) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Dopamine receptor D2L/neurotensin receptor NTS1
Name:Dopamine receptor D2L/neurotensin receptor NTS1
Synonyms:DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like
Type:Cell-surface receptors
Mol. Mass.:50647.10
Organism:Homo sapiens (Human)
Description:P14416
Residue:443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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  Blast E-value cutoff:
BDBM50056443
NameBDBM50056443
Synonyms:(R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one | CHEMBL419792 | PNU-95666E
TypeSmall organic molecule
Emp. Form.C11H13N3O
Mol. Mass.203.2404
SMILESCN[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
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