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TargetTransmembrane domain-containing protein TMIGD3
LigandBDBM50236794
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1661723
Ki 156±n/a nM
Citation Tosh, DKJanowsky, AEshleman, AJWarnick, EGao, ZGChen, ZGizewski, EAuchampach, JASalvemini, DJacobson, KA Scaffold Repurposing of Nucleosides (Adenosine Receptor Agonists): Enhanced Activity at the Human Dopamine and Norepinephrine Sodium Symporters. J Med Chem60:3109-3123 (2017) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Transmembrane domain-containing protein TMIGD3
Name:Transmembrane domain-containing protein TMIGD3
Synonyms:TMIGD3 | Transmembrane domain-containing protein TMIGD3
Type:PROTEIN
Mol. Mass.:30335.79
Organism:Homo sapiens (Human)
Description:ChEMBL_114868
Residue:266
Sequence:
MEGSPAGPIEQKEARWESSWEEQPDWTLGCLSPESQFRIPGLPGCILSFQLKVCFLPVMW
LFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYKNHPKYWCRGYFRDYCNIIAF
SPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRDFARDDMDFTELIVTDDKGTLA
NDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQR
NRRVGNTLKPFSRVLTPKEMAPTEQM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50236794
NameBDBM50236794
Synonyms:CHEMBL4081828
TypeSmall organic molecule
Emp. Form.C21H22ClN7O3S
Mol. Mass.487.962
SMILES[H][C@]12C[C@]1([C@@H](O)[C@@H](O)[C@@H]2n1cnc2c(NC)nc(nc12)C#Cc1ccc(Cl)s1)C(=O)NCCN |r|
Structure
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