Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50237778
Substrate
n/a
Meas. Tech.
ChEMBL_1661884 (CHEMBL4011496)
Ki
1.9±n/a nM
Citation
 Yu, J; Zhao, LX; Park, J; Lee, HW; Sahu, PK; Cui, M; Moss, SM; Hammes, E; Warnick, E; Gao, ZG; Noh, M; Choi, S; Ahn, HC; Choi, J; Jacobson, KA; Jeong, LS N J Med Chem 60:3422-3437 (2017) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50237778
Synonyms:
CHEMBL4103705
Type:
Small organic molecule
Emp. Form.:
C14H17ClN6O3Se
Mol. Mass.:
431.74
SMILES:
CNC(=O)[C@H]1[Se][C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CC3)nc(Cl)nc12 |r|
Structure:
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