Reaction Details Report a problem with these data
Target
Melanocortin receptor 5
Ligand
BDBM82414
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2964
Citation
 Schiöth, HB; Muceniece, R; Wikberg, JE Characterisation of the melanocortin 4 receptor by radioligand binding. Pharmacol Toxicol 79:161-5 (1996) [PubMed]  Article 
Target
Name:
Melanocortin receptor 5
Synonyms:
MC-2 | MC5-R | MC5R | MC5R_HUMAN | Melanocortin MC5 | Melanocortin receptor (M4 and M5) | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R)
Type:
Enzyme
Mol. Mass.:
36612.92
Organism:
Homo sapiens (Human)
Description:
P33032
Residue:
325
Sequence:
MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD
  
Inhibitor
Name:
BDBM82414
Synonyms:
delta MSH
Type:
Small organic molecule
Emp. Form.:
C37H57N11O11S
Mol. Mass.:
863.981
SMILES:
CSCC[C@H](NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,wU:46.45,31.30,15.14,8.8,wD:24.23,4.4,(-14.05,.99,;-14.79,2.35,;-14.03,3.65,;-14.77,5,;-14.01,6.33,;-14.74,7.71,;-16.26,7.73,;-17.05,6.43,;-17.04,9.09,;-18.56,9.11,;-16.24,10.41,;-17.01,11.74,;-12.42,6.34,;-11.64,7.66,;-11.63,5.05,;-10.09,5.12,;-9.32,6.45,;-9.72,7.94,;-9.32,9.43,;-7.83,9.82,;-10.09,10.76,;-9.33,3.79,;-10.05,2.47,;-7.8,3.75,;-7.06,2.39,;-7.8,1.04,;-7.06,-.28,;-9.29,.64,;-5.47,2.4,;-4.71,3.73,;-4.68,1.11,;-3.12,1.18,;-2.74,2.6,;-1.26,3,;-.86,4.48,;.63,4.88,;1.03,6.37,;-.06,7.46,;2.52,6.77,;-2.31,-.1,;-3.02,-1.45,;-.79,-.03,;.06,-1.28,;1.63,-1.23,;2.31,.16,;2.5,-2.47,;3.95,-2.35,;4.73,-.92,;6.15,-.69,;7.25,-1.9,;8.72,-1.33,;8.53,.26,;9.57,1.37,;9.12,2.85,;7.6,3.13,;6.56,2.06,;7.01,.55,;4.9,-3.56,;6.39,-3.25,;4.09,-5.13,)|
Structure:
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