Reaction Details Report a problem with these data
Target
Melanocortin receptor 5
Ligand
BDBM82413
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2958
Citation
 Schiöth, HB; Muceniece, R; Wikberg, JE Characterisation of the melanocortin 4 receptor by radioligand binding. Pharmacol Toxicol 79:161-5 (1996) [PubMed]  Article 
Target
Name:
Melanocortin receptor 5
Synonyms:
MC-2 | MC5-R | MC5R | MC5R_HUMAN | Melanocortin MC5 | Melanocortin receptor (M4 and M5) | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R)
Type:
Enzyme
Mol. Mass.:
36612.92
Organism:
Homo sapiens (Human)
Description:
P33032
Residue:
325
Sequence:
MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD
  
Inhibitor
Name:
BDBM82413
Synonyms:
CAS_72711-43-4 | GAMMA-MSH | Gamma2-MSH
Type:
Small organic molecule
Emp. Form.:
C74H99N21O16S
Mol. Mass.:
1570.774
SMILES:
CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O |r,wU:64.66,86.90,42.43,8.8,wD:78.82,53.55,97.101,32.32,4.4,12.12,(-14.05,.99,;-14.79,2.35,;-14.03,3.65,;-14.77,5,;-14.01,6.33,;-14.74,7.71,;-16.26,7.73,;-17.05,6.43,;-17.04,9.09,;-18.56,9.11,;-19.32,10.42,;-18.57,11.81,;-20.87,10.42,;-21.62,11.76,;-21.65,9.02,;-20.87,7.69,;-21.62,6.34,;-20.84,5.03,;-19.27,5.05,;-18.54,3.73,;-18.56,6.43,;-19.33,7.69,;-16.24,10.41,;-17.02,11.76,;-14.7,10.37,;-12.42,6.34,;-11.64,7.66,;-11.63,5.05,;-10.09,5.12,;-9.33,3.79,;-10.05,2.47,;-7.8,3.75,;-7.06,2.39,;-7.8,1.04,;-7.06,-.28,;-5.54,-.43,;-5.13,-1.9,;-6.42,-2.71,;-7.65,-1.76,;-5.47,2.4,;-4.71,3.73,;-4.68,1.11,;-3.12,1.18,;-2.36,2.54,;-.86,2.59,;-.16,3.96,;1.39,3.98,;2.27,2.71,;1.55,1.33,;-.01,1.31,;-2.31,-.1,;-3.02,-1.45,;-.79,-.03,;.06,-1.28,;-.63,-2.68,;.27,-3.99,;-.44,-5.36,;.51,-6.64,;-.15,-7.99,;.77,-9.27,;-1.62,-8.21,;1.63,-1.23,;2.31,.16,;2.5,-2.47,;3.95,-2.35,;4.73,-.92,;6.15,-.69,;7.25,-1.9,;8.72,-1.33,;8.53,.26,;9.57,1.37,;9.12,2.85,;7.6,3.13,;6.56,2.06,;7.01,.55,;4.9,-3.56,;4.09,-5.13,;6.39,-3.25,;7.42,-4.37,;6.98,-5.86,;8.03,-6.98,;9.52,-6.64,;7.53,-8.52,;8.96,-4.04,;9.41,-2.59,;10,-5.13,;11.45,-4.77,;11.9,-3.27,;13.46,-2.92,;13.89,-1.45,;15.43,-1.18,;15.91,.29,;17.43,.59,;14.96,1.44,;12.56,-5.88,;12.13,-7.38,;14.05,-5.51,;15.12,-6.64,;14.7,-8.12,;15.76,-9.23,;17.28,-8.9,;18.37,-10.04,;17.92,-11.48,;16.4,-11.81,;15.32,-10.7,;16.6,-6.26,;17.04,-4.81,;17.64,-7.35,;19.13,-6.97,;20.17,-8.09,;21.65,-7.76,;19.73,-9.54,)|
Structure:
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