Reaction Details Report a problem with these data
Target
D(4) dopamine receptor
Ligand
BDBM50020680
Substrate
n/a
Ki
873±n/a nM
Comments
PDSP_1613
Citation
 Newman-Tancredi, A; Audinot, V; Chaput, C; Verrièle, L; Millan, MJ [35S]Guanosine-5'-O-(3-thio)triphosphate binding as a measure of efficacy at human recombinant dopamine D4.4 receptors: actions of antiparkinsonian and antipsychotic agents. J Pharmacol Exp Ther 282:181-91 (1997) [PubMed] 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50020680
Synonyms:
4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one | CHEMBL589 | ROPINIROLE
Type:
Small organic molecule
Emp. Form.:
C16H24N2O
Mol. Mass.:
260.3746
SMILES:
CCCN(CCC)CCc1cccc2NC(=O)Cc12
Structure:
Search PDB for entries with ligand similarity: