Reaction Details Report a problem with these data
Target
Prostacyclin receptor
Ligand
BDBM85181
Substrate
n/a
Ki
16±n/a nM
Comments
PDSP_348
Citation
 Kiriyama, M; Ushikubi, F; Kobayashi, T; Hirata, M; Sugimoto, Y; Narumiya, S Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol 122:217-24 (1997) [PubMed]  Article 
Target
Name:
Prostacyclin receptor
Synonyms:
PI2R_MOUSE | Prostacyclin receptor | Prostaglandin I | Prostaglandin I2 | Ptgir
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44475.65
Organism:
MOUSE
Description:
Prostaglandin I2 PTGIR MOUSE::P43252
Residue:
415
Sequence:
MMASDGHPGPPSVTPGSPLSAGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNGLALGILGARRRSHPSAFAVLVTGLAVTDLLGTCFLSPAVFVAYARNSSLLGLAHGGTMLCDTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARFALPSIYAFCCLFCSLPLLGLGEHQQYCPGSWCFIRMRSAQPGGCAFSLAYASLMALLVTSIFFCNGSVTLSLYHMYRQQRRHHGSFVPTSRAREDEVYHLILLALMTVIMAVCSLPLMIRGFTQAIAPDSREMGDLLAFRFNAFNPILDPWVFILFRKAVFQRLKFWLCCLCARSVHGDLQAPLSRPASGRRDPPAPTSLQAKEGSWVPLSSWGTGQVAPLTAVPLTGGDGCSVGMPSKSEAIAACSLC
  
Inhibitor
Name:
BDBM85181
Synonyms:
BERAPROST | CAS_2352 | NSC_2352
Type:
Small organic molecule
Emp. Form.:
C24H30O5
Mol. Mass.:
398.492
SMILES:
CC#CCC(C)C(O)C=CC1C(O)CC2Oc3c(cccc3CCCC(O)=O)C12 |w:8.7|
Structure:
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