Reaction Details
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Melatonin receptor type 1A
Ligand
BDBM85065
Substrate
n/a
Ki
933.25±n/a nM
Comments
PDSP_1123
Citation
Beresford, IJ; Browning, C; Starkey, SJ; Brown, J; Foord, SM; Coughlan, J; North, PC; Dubocovich, ML; Hagan, RM GR196429: a nonindolic agonist at high-affinity melatonin receptors. J Pharmacol Exp Ther 285:1239-45 (1998) [PubMed] More Info.:
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTR1A_PIG | Melatonin | Melatonin receptor type 1A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
17908.30
Organism:
GUINEA PIG
Description:
Melatonin 0 GUINEA PIG::O02781
Residue:
154
Sequence:
YCYICHSLKYDRWYSNRNSLCCVFLICVLTLVAIVPNLCMGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMVIVIFRYLRIWVLVLQIRWRAKPENNPRLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMAPRIPEWLFVA
Inhibitor
Name:
BDBM85065
Synonyms:
CAS_117946-91-5 | Luzindole | NSC_122162
Type:
Small organic molecule
Emp. Form.:
C19H20N2O
Mol. Mass.:
292.3749
SMILES:
CC(=O)NCCc1c(Cc2ccccc2)[nH]c2ccccc12
Structure:
