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Target
Melatonin receptor type 1A
Ligand
BDBM50043289
Substrate
n/a
Ki
0.46±n/a nM
Comments
PDSP_1195
Citation
 Beresford, IJ; Browning, C; Starkey, SJ; Brown, J; Foord, SM; Coughlan, J; North, PC; Dubocovich, ML; Hagan, RM GR196429: a nonindolic agonist at high-affinity melatonin receptors. J Pharmacol Exp Ther 285:1239-45 (1998) [PubMed] 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTR1A_PIG | Melatonin | Melatonin receptor type 1A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
17908.30
Organism:
GUINEA PIG
Description:
Melatonin 0 GUINEA PIG::O02781
Residue:
154
Sequence:
YCYICHSLKYDRWYSNRNSLCCVFLICVLTLVAIVPNLCMGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMVIVIFRYLRIWVLVLQIRWRAKPENNPRLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMAPRIPEWLFVA
  
Inhibitor
Name:
BDBM50043289
Synonyms:
CHEMBL34730 | N-[2-(6-Chloro-5-methoxy-1H-indol-3-yl)-ethyl]-acetamide | N-[2-(6-Chloro-5-methoxy-1H-indol-3-yl)-ethyl]-acetamide(6-Chloromelatonin) | melatonin, 6-Chloro
Type:
Small organic molecule
Emp. Form.:
C13H15ClN2O2
Mol. Mass.:
266.723
SMILES:
COc1cc2c(CCNC(C)=O)c[nH]c2cc1Cl
Structure:
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