Reaction Details
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Alpha-1A adrenergic receptor
Ligand
BDBM30712
Substrate
n/a
Ki
31.62±n/a nM
Comments
PDSP_1428
Citation
Wikberg-Matsson, A; Wikberg, JE; Uhlén, S Characterization of alpha1-adrenoceptor subtypes in the pig. Eur J Pharmacol 347:301-9 (1998) [PubMed] Article More Info.:
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
ADA1A_CAVPO | ADRA1A | adrenergic Alpha1A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51603.72
Organism:
PIG
Description:
adrenergic Alpha1A ADRA1A PIG::Q9WU25
Residue:
466
Sequence:
MVFLSGNASDSSNCTQPPAPVNIPKAILLGVILGVLILFGVPGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMSLCIISIDRYIGVSYPLRYPTIVTQRRGLRALLCLWALSLVISIGPLFGWRQPAPQDETICQINEDPSYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLTSGLKTDKSDSEQVTLRIHRKNAPLGGSGVASSKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLKIQCLRRKQSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYKISKTDGVCEWKFFSSMPRGSARITVPKDQSACTTARVRSKSFLQVCCCVGPSTPNPGENHQVPTIKIHTISLSENGEEV
Inhibitor
Name:
BDBM30712
Synonyms:
6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride | 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride | 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride | MLS000038040 | Oxymetazoline | SMR000059324 | cid_66259
Type:
Small organic molecule
Emp. Form.:
C16H24N2O
Mol. Mass.:
260.3746
SMILES:
Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C |t:11|
Structure:
