Reaction Details
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Alpha-1A adrenergic receptor
Ligand
BDBM50033112
Substrate
n/a
Ki
31.62±n/a nM
Comments
PDSP_181
Citation
Wikberg-Matsson, A; Wikberg, JE; Uhlén, S Characterization of alpha1-adrenoceptor subtypes in the pig. Eur J Pharmacol 347:301-9 (1998) [PubMed] Article More Info.:
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
ADA1A_CAVPO | ADRA1A | adrenergic Alpha1A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51603.72
Organism:
PIG
Description:
adrenergic Alpha1A ADRA1A PIG::Q9WU25
Residue:
466
Sequence:
MVFLSGNASDSSNCTQPPAPVNIPKAILLGVILGVLILFGVPGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMSLCIISIDRYIGVSYPLRYPTIVTQRRGLRALLCLWALSLVISIGPLFGWRQPAPQDETICQINEDPSYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLTSGLKTDKSDSEQVTLRIHRKNAPLGGSGVASSKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLKIQCLRRKQSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYKISKTDGVCEWKFFSSMPRGSARITVPKDQSACTTARVRSKSFLQVCCCVGPSTPNPGENHQVPTIKIHTISLSENGEEV
Inhibitor
Name:
BDBM50033112
Synonyms:
6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propylamino}-1,3,5-trimethyl-1H-pyrimidine-2,4-dione | CHEMBL420060 | Urapidil-5-methyl
Type:
Small organic molecule
Emp. Form.:
C21H31N5O3
Mol. Mass.:
401.5025
SMILES:
COc1ccccc1N1CCN(CCCNc2c(C)c(=O)n(C)c(=O)n2C)CC1
Structure:
