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Target
Delta-type opioid receptor
Ligand
BDBM50013388
Substrate
n/a
Ki
0.3±n/a nM
Comments
PDSP_414
Citation
 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications. NIDA Res Monogr 178:440-66 (1998) [PubMed] 
Target
Name:
Delta-type opioid receptor
Synonyms:
Delta opioid receptor | Delta-type opioid receptor | OPIATE Delta | OPRD1 | OPRD_PIG
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25736.90
Organism:
GUINEA PIG
Description:
OPIATE Delta OPRD1 GUINEA PIG::P79291
Residue:
228
Sequence:
GIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILVITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
  
Inhibitor
Name:
BDBM50013388
Synonyms:
6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol | BREMAZOCINE(-) | Bremazocine | CHEMBL350384
Type:
Small organic molecule
Emp. Form.:
C20H29NO2
Mol. Mass.:
315.4498
SMILES:
CCC12CCN(CC3(O)CC3)C(Cc3ccc(O)cc13)C2(C)C |TLB:6:5:20:19.13.12|
Structure:
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