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Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM50007406
Substrate
n/a
Ki
22±n/a nM
Comments
PDSP_1808
Citation
 Herrick-Davis, K; Grinde, E; Gauthier, C; Teitler, M Pharmacological characterization of the constitutively activated state of the serotonin 5-HT2C receptor. Ann N Y Acad Sci 861:140-5 (1998) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
Type:
Enzyme
Mol. Mass.:
51935.10
Organism:
Rattus norvegicus (Rat)
Description:
P08909
Residue:
460
Sequence:
MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
  
Inhibitor
Name:
BDBM50007406
Synonyms:
1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Trifluoromethyl-phenyl)-piperazine | 1-(3-Trifluoromethyl-phenyl)-piperazine(TFMPP) | CHEMBL274866 | TFMPP
Type:
Small organic molecule
Emp. Form.:
C11H13F3N2
Mol. Mass.:
230.2295
SMILES:
FC(F)(F)c1cccc(c1)N1CCNCC1
Structure:
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