Reaction Details
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5-hydroxytryptamine receptor 4
Ligand
BDBM85607
Substrate
n/a
Ki
10±n/a nM
Comments
PDSP_1699
Citation
Bender, E; Pindon, A; van Oers, I; Zhang, YB; Gommeren, W; Verhasselt, P; Jurzak, M; Leysen, J; Luyten, W Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variant. J Neurochem 74:478-89 (2000) [PubMed] Article More Info.:
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
5-HT-4 | 5-HT4 | 5-HT4S | 5-HT4a | 5-HT4b | 5-HT4c | 5-HT4d | 5-HT4hb | 5-hydroxytryptamine receptor 4 | 5-hydroxytryptamine receptor 4 (5-HT4) | 5HT4R_HUMAN | HTR4 | Serotonin (5-HT) receptor | Serotonin (5-HT3) receptor | Serotonin 4 (5-HT4) receptor | Serotonin Receptor 4
Type:
Enzyme
Mol. Mass.:
43767.54
Organism:
Homo sapiens (Human)
Description:
Q13639
Residue:
388
Sequence:
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT
Inhibitor
Name:
BDBM85607
Synonyms:
CAS_189188-57-6 | SDZ-HTF-919 | SDZ-HTF919
Type:
Small organic molecule
Emp. Form.:
C15H21N5O2
Mol. Mass.:
303.3595
SMILES:
COc1ccc2[nH]cc(C=NN=C(N)NCCCCO)c2c1 |w:9.8,11.10|
Structure:
