Reaction Details
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Report a problem with these dataTarget
Adenosine receptor A3
Ligand
BDBM50006730
Substrate
n/a
Ki
1.13±n/a nM
Comments
PDSP_1618
Citation
Durand, IH; Green, RD Cloning of a chick A3 adenosine receptor: characterization of ligand binding and receptor-effector coupling of chick A1 and A3 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol 363:81-6 (2001) [PubMed] Article More Info.:
Target
Name:
Adenosine receptor A3
Synonyms:
ADENOSINE A3 | ADORA3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37723.59
Organism:
Chick
Description:
A0A8V1ACC1
Residue:
338
Sequence:
MCPQGSPCPASSSPINVTFNTSQVMGSIDVIYISAECLVALLAALGNIPVVWAVKLNAAFHNTTMYFIASLALADIAVGVFVVPLAVLVSLQVSIPFHFCLFLCCLMVVFTQASILSLLAIAIDRYLRVKLPIRYKIISTERRIWGALGLCWSLSLLVGLTPMFGWNKQRSAPYHTCGFTSVIRMDYMVYFSFFAWTLIPLSIMCALYVAVFYIIRTKLSQGATGARGAGTFYGKEFRKAKSLALILFLFAVSWLPLCIMNCVLYFHPEYKIPKPWIFLGILLSHANSAMNPVVYACKIKKFKTTYLLILRTYILCRKKPQAMPSSYRLNTPAVVDTE
Inhibitor
Name:
BDBM50006730
Synonyms:
(R)-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | (R-PIa) 2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | (S)-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | 2-(hydroxymethyl)-5-{6-[(1-phenylpropan-2-yl)amino]-9H-purin-9-yl}oxolane-3,4-diol | 2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | CHEMBL274022 | ChEMBL_20163 | D-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | L-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | R-N6-(2-phenylisopropyl) adenosine | R-PIA | S-PIA
Type:
Small organic molecule
Emp. Form.:
C19H23N5O4
Mol. Mass.:
385.417
SMILES:
CC(Cc1ccccc1)Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1O
Structure:
