Reaction Details Report a problem with these data
Target
Calcium-activated potassium channel subunit beta-1
Ligand
BDBM84745
Substrate
n/a
Ki
1000±n/a nM
Comments
PDSP_763
Citation
 Bymaster, FP; Dreshfield-Ahmad, LJ; Threlkeld, PG; Shaw, JL; Thompson, L; Nelson, DL; Hemrick-Luecke, SK; Wong, DT Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology 25:871-80 (2001) [PubMed]  Article 
Target
Name:
Calcium-activated potassium channel subunit beta-1
Synonyms:
Calcium-activated potassium channel subunit beta-1 | KCMB1_RAT | Kcnmb1 | Potassium Channel (Ca2+ dependent)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21917.35
Organism:
RAT
Description:
Potassium Channel (Ca2+ dependent) 0 RAT::P97678
Residue:
191
Sequence:
MGKKLVMAQKRGETRALCLGVAMVVCAAITYYILGTTVLPLYQKSVWTQESTCHLVETNIKDQEELEGRKVPQYPCLWVNVSAVGRWAMLYHTEDTRDQNQQCSYIPRNLDNYQTALVDVKKVRANFYKHHNFYCFSAPQVNETSVVYQRLYGPQILLFSFFWPTFLLTGGLLIIAMVKLNRSLSVLAAQK
  
Inhibitor
Name:
BDBM84745
Synonyms:
CAS_136434-34-9 | DULOXETINE | LY-248686 | LY248686 | USRE49340, Rank 5
Type:
Small organic molecule
Emp. Form.:
C18H19NOS
Mol. Mass.:
297.415
SMILES:
CNCC[C@H](Oc1cccc2ccccc12)c1cccs1 |r|
Structure:
Search PDB for entries with ligand similarity: