Reaction Details Report a problem with these data
Target
Nicotinic acetylcholine receptor
Ligand
BDBM35226
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2048
Citation
 Miller, DK; Wong, EH; Chesnut, MD; Dwoskin, LP Reboxetine: functional inhibition of monoamine transporters and nicotinic acetylcholine receptors. J Pharmacol Exp Ther 302:687-95 (2002) [PubMed]  Article 
Target
Name:
Nicotinic acetylcholine receptor
Synonyms:
Nicotinic acetylcholine receptor | n-AChR
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2478.99
Organism:
RAT
Description:
n-AChR 0 RAT::Q62594
Residue:
23
Sequence:
MTMALLGTLLLLALFGRSQGKNE
  
Inhibitor
Name:
BDBM35226
Synonyms:
(S,S)-reboxetine | Reboxetine | Vestra
Type:
Small organic molecule
Emp. Form.:
C19H23NO3
Mol. Mass.:
313.3908
SMILES:
CCOc1ccccc1O[C@H]([C@@H]1CNCCO1)c1ccccc1 |r|
Structure:
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