Reaction Details Report a problem with these data
Target
Ionotropic glutamate receptor subunit Delta2
Ligand
BDBM8961
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_3009
Citation
 Williams, K; Dattilo, M; Sabado, TN; Kashiwagi, K; Igarashi, K Pharmacology of delta2 glutamate receptors: effects of pentamidine and protons. J Pharmacol Exp Ther 305:740-8 (2003) [PubMed]  Article 
Target
Name:
Ionotropic glutamate receptor subunit Delta2
Synonyms:
Glutamate delta 2 | Glutamate receptor delta-2 subunit
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19076.25
Organism:
Xenopus
Description:
B9V8R6
Residue:
168
Sequence:
FDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTISRIESSIQSLQDLSRQTDIPYGTVFDSAVYEHVRVKGMNPFERDSMYSQMWRMINRSNGSENNVQESLEGIQKV
  
Inhibitor
Name:
BDBM8961
Synonyms:
1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrahydroacridin-9-amine | 9-THA | 9-amino-1,2,3,4-tetrahydroacridine (THA) | CHEMBL1337960 | CHEMBL95 | Cognex | Tacrine | Tracine | US8999994, Tacrine | cid_1935 | tacrine.HCl
Type:
Small organic molecule
Emp. Form.:
C13H14N2
Mol. Mass.:
198.2637
SMILES:
Nc1c2CCCCc2nc2ccccc12
Structure:
Search PDB for entries with ligand similarity: