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TargetADRA1B
LigandBDBM50160165
Substrate/Competitorn/a
Ki 16±n/a nM
CommentsPDSP_6219
Citation Kinsella, GKRozas, IWatson, GW Computational study of antagonist/alpha1A adrenoceptor complexes--observations of conformational variations on the formation of ligand/receptor complexes. J Med Chem49:501-10 (2006) [PubMed]  Article
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ADRA1B
Name:ADRA1B
Synonyms:Adra1b protein | adrenergic Alpha1B
Type:Enzyme Catalytic Domain
Mol. Mass.:50983.17
Organism:Mus musculus
Description:Q05D47
Residue:462
Sequence:
MNPDLDTGHNTSAPAHWGELKDANFTGPNQTSSNSTLPQLDVTRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAIADLLLSFTVLPFSATLEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFM
RILGCQCRGGRRRRRRRRLGGCAYTYRPWTRGGSLERSQSPKDSLDDSGSCMSGSQRTLP
SASPSPGYLGLGTQPPVELCASPEWKPGALLSLPEPPGRRGR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50160165
NameBDBM50160165
Synonyms:CHEMBL88272 | RS-17053 | [2-(2-Cyclopropylmethoxy-phenoxy)-ethyl]-[2-(1H-indol-3-yl)-1,1-dimethyl-ethyl]-amine | [2-(5-Chloro-1H-indol-3-yl)-1,1-dimethyl-ethyl]-[2-(2-cyclopropylmethoxy-phenoxy)-ethyl]-amine
TypeSmall organic molecule
Emp. Form.C24H29ClN2O2
Mol. Mass.412.952
SMILESCC(C)(Cc1c[nH]c2ccc(Cl)cc12)NCCOc1ccccc1OCC1CC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a