Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89043
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen.
IC50
1090±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89043
Synonyms:
4-butoxybenzoic acid [(Z)-[amino-(3-bromophenyl)methylene]amino] ester | 4-butoxybenzoic acid [(Z)-[amino-(3-bromophenyl)methylidene]amino] ester | MLS-0454713.0001 | [(Z)-[amino-(3-bromophenyl)methylidene]amino] 4-butoxybenzoate | [(Z)-[azanyl-(3-bromophenyl)methylidene]amino] 4-butoxybenzoate | cid_9567416
Type:
Small organic molecule
Emp. Form.:
C18H19BrN2O3
Mol. Mass.:
391.259
SMILES:
CCCCOc1ccc(cc1)C(=O)ON=C(N)c1cccc(Br)c1 |w:14.14|
Structure:
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