Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89056
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen.
IC50
2100±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89056
Synonyms:
2-(4-bromo-3-methyl-phenoxy)acetic acid [(Z)-[1-amino-2-(4-chlorophenyl)ethylidene]amino] ester | 2-(4-bromo-3-methylphenoxy)acetic acid [(Z)-[1-amino-2-(4-chlorophenyl)ethylidene]amino] ester | MLS-0454725.0001 | [(Z)-[1-amino-2-(4-chlorophenyl)ethylidene]amino] 2-(4-bromo-3-methylphenoxy)acetate | [(Z)-[1-azanyl-2-(4-chlorophenyl)ethylidene]amino] 2-(4-bromanyl-3-methyl-phenoxy)ethanoate | cid_9660646
Type:
Small organic molecule
Emp. Form.:
C17H16BrClN2O3
Mol. Mass.:
411.678
SMILES:
Cc1cc(OCC(=O)ON=C(N)Cc2ccc(Cl)cc2)ccc1Br |w:9.8|
Structure:
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