Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89059
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen.
IC50
1370±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89059
Synonyms:
MLS-0454728.0001 | [(Z)-[amino-(3-fluoro-4-methylphenyl)methylidene]amino] benzoate | [(Z)-[azanyl-(3-fluoranyl-4-methyl-phenyl)methylidene]amino] benzoate | benzoic acid [(Z)-[amino-(3-fluoro-4-methyl-phenyl)methylene]amino] ester | benzoic acid [(Z)-[amino-(3-fluoro-4-methylphenyl)methylidene]amino] ester | cid_9581171
Type:
Small organic molecule
Emp. Form.:
C15H13FN2O2
Mol. Mass.:
272.2743
SMILES:
Cc1ccc(cc1F)C(N)=NOC(=O)c1ccccc1 |w:10.11|
Structure:
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