Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM77767
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen.
IC50
4480±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM77767
Synonyms:
MLS000723710 | N'-[(1E,2Z)-3-(2-furyl)prop-2-enylidene]thiophene-2-carbohydrazide | N-[[(Z)-3-(2-furanyl)prop-2-enylidene]amino]-2-thiophenecarboxamide | N-[[(Z)-3-(2-furyl)prop-2-enylidene]amino]thiophene-2-carboxamide | N-[[(Z)-3-(furan-2-yl)prop-2-enylidene]amino]thiophene-2-carboxamide | SMR000305305 | cid_1584401
Type:
Small organic molecule
Emp. Form.:
C12H10N2O2S
Mol. Mass.:
246.285
SMILES:
O=C(NN=C\C=C/c1ccco1)c1cccs1
Structure:
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