Reaction Details
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Cathepsin G
Ligand
BDBM113248
Substrate
n/a
Meas. Tech.
Cathepsin G Assay
pH
7.2±n/a
Temperature
310.15±n/a K
Ki
1900±n/a nM
Comments
extracted
Citation
Wagberg, F; Leonardsson, G Benzoxazinone derivatives for treatment of skin diseases US Patent US9695194 Publication Date 7/4/2017 More Info.:
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
Inhibitor
Name:
BDBM113248
Synonyms:
US9695194, 7
Type:
Small organic molecule
Emp. Form.:
C17H12ClNO4
Mol. Mass.:
329.734
SMILES:
Clc1ccccc1-c1nc2cc3OCCCOc3cc2c(=O)o1
Structure:
