Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM50289001
Substrate
n/a
Meas. Tech.
Cathepsin G Assay
pH
7.2±n/a
Temperature
310.15±n/a K
Ki
1900±n/a nM
Comments
extracted
Citation
 Wagberg, F; Leonardsson, G Benzoxazinone derivatives for treatment of skin diseases US Patent  US9695194 Publication Date 7/4/2017 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM50289001
Synonyms:
2-(2-Iodo-phenyl)-6,7-dimethoxy-benzo[d][1,3]oxazin-4-one | CHEMBL349763 | US9695194, 18
Type:
Small organic molecule
Emp. Form.:
C16H12INO4
Mol. Mass.:
409.1753
SMILES:
COc1cc2nc(oc(=O)c2cc1OC)-c1ccccc1I
Structure:
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