Reaction Details Report a problem with these data
Target
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Ligand
BDBM92459
Substrate
n/a
Meas. Tech.
SPA Assay
pH
7.3±0
Temperature
295.15±0 K
IC50
>200000±0 nM
Citation
 Niu, X; Fan, X; Sun, J; Ting, P; Narula, S; Lundell, D Inhibition of fucosyltransferase VII by gallic acid and its derivatives. Arch Biochem Biophys 425:51-7 (2004) [PubMed]  Article 
Target
Name:
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Synonyms:
Alpha-(2,3)-(N)-sialyltransferase | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | SIA4A_HUMAN | SIAT4 | SIAT4A | ST3GAL1
Type:
n/a
Mol. Mass.:
39090.19
Organism:
Homo sapiens (Human)
Description:
Q11201
Residue:
340
Sequence:
MVTLRKRTLKVLTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLKRLIKHRPCTCTHCIGQRKLSAWFDERFNQTMQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTIKELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPAKIRVKQDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWHHYWENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFKGR
  
Inhibitor
Name:
BDBM92459
Synonyms:
CHEMBL384759 | GDP | Guanosine Diphosphate
Type:
Small molecule
Emp. Form.:
C10H15N5O11P2
Mol. Mass.:
443.2005
SMILES:
Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
Structure:
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