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Target
Translocator protein
Ligand
BDBM279578
Substrate
n/a
Meas. Tech.
[3H]PK 11195 radio-assay
Ki
380±n/a nM
Citation
 Gavish, M; Veenman, JA; Shterenberg, A; Marek, I; Vainshtein, A; Avital, A Quinazoline scaffold based compounds, pharmaceutical compositions and methods of use thereof US Patent  US10035780 Publication Date 7/31/2018 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM279578
Synonyms:
US10035780, Compound 2
Type:
Small organic molecule
Emp. Form.:
C19H17ClFN3O2
Mol. Mass.:
373.809
SMILES:
CCN(CC)C(=O)Oc1nc(nc2ccccc12)-c1ccc(F)c(Cl)c1
Structure:
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