Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM41069
Substrate
n/a
IC50
3810±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM41069
Synonyms:
3-Chloro-benzo[b]thiophene-2-carboxylic acid (3-oxazolo[4,5-b]pyridin-2-yl-phenyl)-amide | 3-chloranyl-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]-1-benzothiophene-2-carboxamide | 3-chloro-N-(3-oxazolo[4,5-b]pyridin-2-ylphenyl)benzothiophene-2-carboxamide | 3-chloro-N-[3-(2-oxazolo[4,5-b]pyridinyl)phenyl]-1-benzothiophene-2-carboxamide | 3-chloro-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]-1-benzothiophene-2-carboxamide | MLS000556074 | SMR000177639 | cid_1132506
Type:
Small organic molecule
Emp. Form.:
C21H12ClN3O2S
Mol. Mass.:
405.857
SMILES:
Clc1c(sc2ccccc12)C(=O)Nc1cccc(c1)-c1nc2ncccc2o1
Structure:
Search PDB for entries with ligand similarity: