Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM82682
Substrate
n/a
IC50
10700±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM82682
Synonyms:
MLS000546589 | N'-(3-chlorobenzoyl)thieno[2,3-b]quinoline-2-carbohydrazide | N'-(3-chlorobenzoyl)thieno[2,3-b]quinoline-2-carbohydrazide | N'-(3-chlorophenyl)carbonylthieno[2,3-b]quinoline-2-carbohydrazide | N'-[(3-chlorophenyl)-oxomethyl]-2-thieno[2,3-b]quinolinecarbohydrazide | SMR000179987 | cid_1485302
Type:
Small organic molecule
Emp. Form.:
C19H12ClN3O2S
Mol. Mass.:
381.835
SMILES:
Clc1cccc(c1)C(=O)NNC(=O)c1cc2cc3ccccc3nc2s1
Structure:
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