Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94979
Substrate
n/a
IC50
4510±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94979
Synonyms:
2-thiophenecarboxylic acid [4-[(Z)-[[(4-chlorophenyl)-oxomethyl]hydrazinylidene]methyl]phenyl] ester | MLS000569215 | SMR000176672 | Thiophene-2-carboxylic acid 4-[(4-chloro-benzoyl)-hydrazonomethyl]-phenyl ester | [4-[(Z)-[(4-chlorobenzoyl)hydrazinylidene]methyl]phenyl] thiophene-2-carboxylate | [4-[(Z)-[(4-chlorophenyl)carbonylhydrazinylidene]methyl]phenyl] thiophene-2-carboxylate | cid_5789896 | thiophene-2-carboxylic acid [4-[(Z)-[(4-chlorobenzoyl)hydrazono]methyl]phenyl] ester
Type:
Small organic molecule
Emp. Form.:
C19H13ClN2O3S
Mol. Mass.:
384.836
SMILES:
Clc1ccc(cc1)C(=O)N\N=C/c1ccc(OC(=O)c2cccs2)cc1
Structure:
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