Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94951
Substrate
n/a
IC50
14200±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94951
Synonyms:
(3-Amino-4,6-dimethyl-thieno[2,3-b]pyridin-2-yl)-(3,4-dichloro-phenyl)-methanone | (3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinyl)-(3,4-dichlorophenyl)methanone | (3-amino-4,6-dimethyl-thieno[2,3-b]pyridin-2-yl)-(3,4-dichlorophenyl)methanone | (3-amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3,4-dichlorophenyl)methanone | (3-azanyl-4,6-dimethyl-thieno[2,3-b]pyridin-2-yl)-(3,4-dichlorophenyl)methanone | MLS000589528 | SMR000212965 | cid_3812524
Type:
Small organic molecule
Emp. Form.:
C16H12Cl2N2OS
Mol. Mass.:
351.25
SMILES:
Cc1cc(C)c2c(N)c(sc2n1)C(=O)c1ccc(Cl)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: