Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM73701
Substrate
n/a
IC50
11900±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM73701
Synonyms:
2,6-diamino-5-(2,4-dichlorobenzyl)-4-pyrimidinylamine | 5-[(2,4-dichlorophenyl)methyl]pyrimidine-2,4,6-triamine | MLS000691890 | SMR000333930 | [2,6-diamino-5-(2,4-dichlorobenzyl)pyrimidin-4-yl]amine | cid_3522147
Type:
Small organic molecule
Emp. Form.:
C11H11Cl2N5
Mol. Mass.:
284.145
SMILES:
Nc1nc(N)c(Cc2ccc(Cl)cc2Cl)c(N)n1
Structure:
Search PDB for entries with ligand similarity: