Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94924
Substrate
n/a
IC50
13100±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94924
Synonyms:
6-[2-(4-methoxyanilino)-1,3-thiazol-4-yl]-4H-1,4-benzoxazin-3-one | 6-[2-(4-methoxyanilino)-4-thiazolyl]-4H-1,4-benzoxazin-3-one | 6-[2-(p-anisidino)thiazol-4-yl]-4H-1,4-benzoxazin-3-one | 6-[2-[(4-methoxyphenyl)amino]-1,3-thiazol-4-yl]-4H-1,4-benzoxazin-3-one | MLS001011091 | SMR000353004 | cid_3294683
Type:
Small organic molecule
Emp. Form.:
C18H15N3O3S
Mol. Mass.:
353.395
SMILES:
COc1ccc(Nc2nc(cs2)-c2ccc3OCC(=O)Nc3c2)cc1
Structure:
Search PDB for entries with ligand similarity: