Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM95043
Substrate
n/a
IC50
11500±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM95043
Synonyms:
3-(2,6-dichlorobenzyl)-2-methyl-4(1H)-pyridinone | 3-(2,6-dichlorobenzyl)-2-methyl-4-pyridone | 3-[(2,6-dichlorophenyl)methyl]-2-methyl-1H-pyridin-4-one | 3-[[2,6-bis(chloranyl)phenyl]methyl]-2-methyl-1H-pyridin-4-one | MLS001166028 | SMR000549932 | cid_1488801
Type:
Small organic molecule
Emp. Form.:
C13H11Cl2NO
Mol. Mass.:
268.139
SMILES:
Cc1nccc(O)c1Cc1c(Cl)cccc1Cl
Structure:
Search PDB for entries with ligand similarity: