Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96853
Substrate
n/a
IC50
26949±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96853
Synonyms:
(3S,4aS)-1-[2-(1-cyclohexenyl)ethyl]-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-2-oxo-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylic acid ethyl ester | (3S,4aS)-1-[2-(cyclohexen-1-yl)ethyl]-2-keto-3-[2-keto-2-[2-(2-methoxyphenyl)ethylamino]ethyl]-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylic acid ethyl ester | MLS003674784 | SMR002354080 | cid_53383840 | ethyl (3S,4aS)-1-[2-(cyclohexen-1-yl)ethyl]-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxidanylidene-ethyl]-2-oxidanylidene-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylate | ethyl (3S,4aS)-1-[2-(cyclohexen-1-yl)ethyl]-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-2-oxo-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylate
Type:
Small organic molecule
Emp. Form.:
C31H42N2O5
Mol. Mass.:
522.6756
SMILES:
CCOC(=O)[C@]12CCCC=C1N(CCC1=CCCCC1)C(=O)[C@H](CC(=O)NCCc1ccccc1OC)C2 |c:9,t:15|
Structure:
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