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Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96856
Substrate
n/a
IC50
11804±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96856
Synonyms:
4-(2-methoxyphenyl)-1-[2-(2-methoxyphenyl)ethyl]-5-propan-2-yl-imidazole;2,2,2-tris(fluoranyl)ethanoic acid | 4-(2-methoxyphenyl)-1-[2-(2-methoxyphenyl)ethyl]-5-propan-2-ylimidazole;2,2,2-trifluoroacetic acid | 5-isopropyl-1-(2-methoxyphenethyl)-4-(2-methoxyphenyl)-1H-imidazole | 5-isopropyl-4-(2-methoxyphenyl)-1-[2-(2-methoxyphenyl)ethyl]imidazole;2,2,2-trifluoroacetic acid | MLS003510317 | SMR002158051 | cid_56588127
Type:
Small organic molecule
Emp. Form.:
C22H26N2O2
Mol. Mass.:
350.454
SMILES:
COc1ccccc1CCn1cnc(c1C(C)C)-c1ccccc1OC
Structure:
Search PDB for entries with ligand similarity: