Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96880
Substrate
n/a
IC50
>3323±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96880
Synonyms:
(2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-3-methyl-2-(o-toluoylamino)butanoyl]pyrrolidine-2-carboxamide | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-3-methyl-2-[(2-methylbenzoyl)amino]butanoyl]pyrrolidine-2-carboxamide | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-3-methyl-2-[(2-methylphenyl)carbonylamino]butanoyl]pyrrolidine-2-carboxamide | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-3-methyl-2-[[(2-methylphenyl)-oxomethyl]amino]-1-oxobutyl]-2-pyrrolidinecarboxamide | MLS003777912 | SMR002440892 | cid_53361914
Type:
Small organic molecule
Emp. Form.:
C26H32ClN3O3
Mol. Mass.:
470.004
SMILES:
CC(C)[C@H](NC(=O)c1ccccc1C)C(=O)N1CCC[C@H]1C(=O)NCCc1ccccc1Cl
Structure:
Search PDB for entries with ligand similarity: