Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 0 group B member 1
Ligand
BDBM97359
Substrate
n/a
IC50
>67574±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 0 group B member 1
Synonyms:
AHC | DAX1 | NR0B1 | NR0B1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51729.22
Organism:
Homo sapiens (Human)
Description:
gi_5016090
Residue:
470
Sequence:
MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
  
Inhibitor
Name:
BDBM97359
Synonyms:
3-benzyl-6-bromo-2-(4-methylphenyl)imidazo[1,2-a]pyridine | 3-benzyl-6-bromo-2-(p-tolyl)imidazo[1,2-a]pyridine | 6-bromanyl-2-(4-methylphenyl)-3-(phenylmethyl)imidazo[1,2-a]pyridine | 6-bromo-2-(4-methylphenyl)-3-(phenylmethyl)imidazo[1,2-a]pyridine | MLS003269836 | SMR001835094 | cid_51360054
Type:
Small organic molecule
Emp. Form.:
C21H17BrN2
Mol. Mass.:
377.277
SMILES:
Cc1ccc(cc1)-c1nc2ccc(Br)cn2c1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: