Reaction Details Report a problem with these data
Target
Fucose-binding lectin PA-IIL
Ligand
BDBM103987
Substrate
n/a
IC50
2.938e+5±n/a nM
Citation
 Hauck, D; Joachim, I; Frommeyer, B; Varrot, A; Philipp, B; Möller, HM; Möller, A; Exner, TE; Titz, A Discovery of two classes of potent glycomimetic inhibitors of Pseudomonas aeruginosa LecB with distinct binding modes. ACS Chem Biol 8:1775-84 (2013) [PubMed]  Article 
Target
Name:
Fucose-binding lectin PA-IIL
Synonyms:
LecB | PA-IIL
Type:
Protein
Mol. Mass.:
11857.84
Organism:
Pseudomonas aeruginosa
Description:
Q9HYN5
Residue:
115
Sequence:
MATQGVFTLPANTRFGVTAFANSSGTQTVNVLVNNETAATFSGQSTNNAVIGTQVLNSGSSGKVQVQVSVNGRPSDLVSAQVILTNELNFALVGSEDGTDNDYNDAVVVINWPLG
  
Inhibitor
Name:
BDBM103987
Synonyms:
LecB Inhibitor Triazoles 2e
Type:
Small organic molecule
Emp. Form.:
C16H21N3O5
Mol. Mass.:
335.355
SMILES:
COC1O[C@H](Cn2cc(nn2)-c2ccc(C)cc2)[C@@H](O)C(O)[C@@H]1O |r|
Structure:
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