Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM109700
Substrate
n/a
Meas. Tech.
Inhibition Assay
Ki
0.27±0.0 nM
Citation
 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Heteroarylcarboxylic acid ester derivative US Patent  US8609715 Publication Date 12/17/2013 
Target
Name:
Serine protease 1
Synonyms:
Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1
Type:
Enzyme
Mol. Mass.:
26557.80
Organism:
Homo sapiens (Human)
Description:
P07477
Residue:
247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS
  
Inhibitor
Name:
BDBM109700
Synonyms:
US8609715, B-57
Type:
Small organic molecule
Emp. Form.:
C23H18FN3O7S
Mol. Mass.:
499.468
SMILES:
NC(=N)c1ccc(OC(=O)c2ccc(s2)-c2ccc(cc2)C(=O)N[C@@H](CC(O)=O)C(O)=O)c(F)c1 |r|
Structure:
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